In their 12th season, the Winchester brothers have added yet another victory to their list of achievements.

(This one comes right after stopping the apocalypse.)

The coroners van just pulled into the driveway.

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Credit: MATTHIAS CLAMER for EW

Turns out the only thing harder to kill than the Winchesters is the show itself.

Its been an unsung hero.

Seriously, how many nights have they spent sleeping in their car?

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Our shows not bound by reality, Ackles says.

Were rooted in reality but were not bound by it.

I think that gives us a fifth wall almost.

No matter how meta or abstract the ideas get God has a sister!

one thing remains unchanged.

This is a show about two brothers.

His plan: Get back to basics.

Youre going to see two brothers be sons, Ackles says.

[This season is] more Sam and Dean on the road.

Crowley is there, Dabb says.

He is pushing them to confront the emotional bomb that is their mother showing up.

I think [Sams] glorified mom so much in his head, Padalecki says.

Its almost like a blind date that Sams already in love with the person he hasnt met yet.

Two hundred forty-one episodes to be exact, and theyre not done yet.

We dont just assume its going to happen, Padalecki says.

If we dont make it to 300, I think Ackles and I will both be truly bummed.

Id like to get to 300 before that day comes.

(The only thing thats certain about Supernaturals end is Babys fate.

He gets Baby, Padalecki says of Ackles.

I get Baby Two.

Ackles makes one correction: No, youll get Three.

It wont be needed this show has a lot of life left in it.

Not that death has ever stopped it before.

A version of this story originally appeared in Entertainment Weekly issue #1431/1432.