She was iconic, my boss, cast mate and a friend and I will miss her.
In a subsequent statement provided to EW, Keaton said, Mary Tyler Moore could light up a room!
She is an icon and a friend.

Credit: Andy Kropa/Getty Images; Elisabetta A. Villa/Getty Images
She was my cast mate and my boss.
She was incredibly funny and completely generous.
She is truly going to be missed.
It was the worst day of my life for an entire summer.
Keaton added, It was unbelievably uncomfortable, was it not?
Watch a clip of Keaton and Letterman onMaryabove, and read morestars reactions to Moores death here.