The show ran on ABC for two years, coming to its untimely end in May 2013.

Pictured above in her 2009 run onScrubsas Dr. Denise Mahoney, Coupe landed her first roles in the mid-2000s.

Elisha Cuthbert

Elisha Cuthbert was the little sister to Coupe inHappy Endings.

‘Happy Endings,’ Then and Now

Craig Sjodin/ABC

Cuthbert took the role more than 10 years into her career.

She made her acting debut in 1996, playing Megan inAre You Afraid of the Dark?

Zachary Knighton

Happy Endingsfound its Dave, the directionless ex-fiance of Alex, in Zachary Knighton.

Eliza Coupe

Michael Ansell/ABC via Getty Images; Karen Neal/ABC via Getty Images

His other early projects include turns inAssassination of a High School President,Taking Woodstock, andSolitary Man.

Pictured above in 2007, Wayans Jr.’s other early credits includeDance FlickandThe Other Guys.

Casey Wilson

Casey Wilson was “amahzing” asHappy Endings' larger-than-life Penny Hartz.

Elisha Cuthbert

Nickelodeon; Peter “Hopper” Stone/ABC via Getty Images

Zachary Knighton

Dimitrios Kambouris/WireImage; Michael Ansell/ABC via Getty Images

Adam Pally

Comedy Central; Bruce Birmelin/ABC via Getty Images

Damon Wayans Jr.

Jeff Kravitz/FilmMagic; Randy Holmes/ABC via Getty Images

Casey Wilson

Dana Edelson/NBC/NBCU Photo Bank; Randy Holmes/ABC via Getty Images