How do you keep a long-running medical drama fresh after 13 seasons?

By literally blowing up the hospital at its center.

The updates lend themselves to a lot of comedy, bringing the show back to its rom-com roots.

089_EW1482THURfolo.pdf

EW

“Those times are behind the hospital.

“You’re going to need a bottle of wine, you’re going to cry duringGrey’s Anatomy.

Do I think there is a happier, lighter, sexier side also?

Absolutely, and you’ll see that just from the two-hour premiere.”

WhereGrey’sis not so light is the show’s most complicated love triangle yet.

Surprisingly, Meredith seems to be handling the situation quite well.

“But it begs the question, well, is she really?”

“Everything was okay if nobody else was in the mix in her mind.

“It’s all painful to be honest.

She needs to stop being in a state of limbo.”

“It also causes issues for Owen’s family.”

Grey’s Anatomyreturns with a two-hour premiere on Thursday at 8 p.m.